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Necrosis
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- Title:
- Dermatology: Warfarin-induced Skin Necrosis, Fatal, Breast
- Description:
- Fatal skin necrosis at breast, induced by heparin. Skin necrosis is the pathologic death of one or more cells, or of a portion of tissue or organ, resulting from irreversible damage; earliest irreversible changesare mitochondrial, consisting of swelling and granular calcium deposits seen by electron microscopy; most frequent visible alterationsare nuclear: pyknosis, shrunken and abnormally dark basophilic staining; karyolysis, swollen and abnormally pale basophilic staining;or karyorrhexis, rupture, and fragmentation of the nucleus. After such changes, the outlines of individual cells are indistinct, andaffected cells may merge, sometimes forming a focus of coarsely granular, amorphous, or hyaline material.
- Keyword:
- skin, Cell death, Pathological Conditions, mitochondrial swelling, cell lysis, Pathologic Processes, Signs and Symptoms
- Subject:
- Breast, Necrosis, Dermatology
- Creator:
- Metropolitan Hospital Center, Kathryn Russel, MD
- Publisher:
- i-Human Patients
- Language:
- English
- Copyright Holder:
- Metropolitan Hospital Center
- Rights:
- http://www.i-human.com/service-agreement-print
- Resource Type:
- Photograph
- Title:
- Dermatology: Skin, Warfarin-induced Skin Necrosis, Fatal
- Description:
- Fatal skin necrosis, induced by heparin. Skin necrosis is the pathologic death of one or more cells, or of a portion of tissue or organ, resulting from irreversible damage; earliest irreversible changesare mitochondrial, consisting of swelling and granular calcium deposits seen by electron microscopy; most frequent visible alterationsare nuclear: pyknosis, shrunken and abnormally dark basophilic staining; karyolysis, swollen and abnormally pale basophilic staining;or karyorrhexis, rupture, and fragmentation of the nucleus. After such changes, the outlines of individual cells are indistinct, andaffected cells may merge, sometimes forming a focus of coarsely granular, amorphous, or hyaline material
- Keyword:
- mitochondrial swelling, Signs and Symptoms, Pathological Conditions, skin, Cell death, Pathologic Processes, cell lysis
- Subject:
- Dermatology, Necrosis
- Creator:
- Metropolitan Hospital Center, Kathryn Russel, MD
- Publisher:
- i-Human Patients
- Language:
- English
- Copyright Holder:
- Metropolitan Hospital Center
- Rights:
- http://www.i-human.com/service-agreement-print
- Resource Type:
- Photograph
- Title:
- Cutaneous Vasculitis With Skin Necrosis, SLE Patient, Image 2
- Description:
- Vasculitis (plural: vasculitides) is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis is sometimes considered a type of vasculitis.[3] Vasculitis is primarily due to leukocyte migration and resultant damage.
- Keyword:
- Cell Physiological Phenomena, Cell Physiological Processes, blood vessels, Vascular Diseases, Inflammation
- Subject:
- Pathologic Processes, Vasculitis, Cardiovascular Diseases, Necrosis, Cell Death, Pathological Conditions, Signs and Symptoms
- Creator:
- Metropolitan Hospital Center, Kathryn Russel, MD
- Publisher:
- Metropolitan Hospital Center
- Language:
- English
- Copyright Holder:
- Metropolitan Hospital Center
- Rights:
- http://www.i-human.com/service-agreement-print
- Resource Type:
- Photo
- Title:
- Cutaneous Vasculitis With Skin Necrosis, SLE Patient, Image 3
- Description:
- Vasculitis (plural: vasculitides) is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis is sometimes considered a type of vasculitis.[3] Vasculitis is primarily due to leukocyte migration and resultant damage.
- Keyword:
- blood vessels, Cell Physiological Processes, Vascular Diseases, Inflammation, Cell Physiological Phenomena
- Subject:
- Cell Death, Necrosis, Cardiovascular Diseases, Vasculitis, Pathological Conditions, Signs and Symptoms, Pathologic Processes
- Creator:
- Metropolitan Hospital Center, Kathryn Russel, MD
- Publisher:
- Metropolitan Hospital Center
- Language:
- English
- Copyright Holder:
- Metropolitan Hospital Center
- Rights:
- http://www.i-human.com/service-agreement-print
- Resource Type:
- Photo
- Title:
- Cutaneous Vasculitis With Skin Necrosis, SLE Patient, Image 1
- Description:
- Vasculitis (plural: vasculitides) is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis is sometimes considered a type of vasculitis.[3] Vasculitis is primarily due to leukocyte migration and resultant damage.
- Keyword:
- blood vessels, Cell Physiological Processes, Cell Physiological Phenomena, Inflammation, Vascular Diseases
- Subject:
- Cell Death, Vasculitis, Pathological Conditions, Signs and Symptoms, Cardiovascular Diseases, Necrosis, Pathologic Processes
- Creator:
- Metropolitan Hospital Center, Kathryn Russel, MD
- Publisher:
- Metropolitan Hospital Center
- Language:
- English
- Copyright Holder:
- Metropolitan Hospital Center
- Rights:
- http://www.i-human.com/service-agreement-print
- Resource Type:
- Photo