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  1. Macrograph: Coronary Artery Atherosclerosis (Images Only)

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    Description: Figure 1. Coronary artery with early atheroma and fibrous cap formation. A. Gross macrophotograph of a longitudinally sectioned coronary artery. L indicates the lumen. The box marks a region with an early atheromatous lesion, as shown in the photomicrograph below it (B). The thin arrow to the right of the box marks a region with a more advanced lesion (see figure 2). B. Microphotograph of the early atheromatous lesion as seen in the boxed area in A. This image shows the full thickness of the coronary artery wall, from adventitia at the bottom to lumen at the top. Layers of the artery are indicated by lowercase letters on the right side of the image: l = lumen, I = intima, m = media, a = adventitia. The two yellow lines on both sides of the image mark the boundary between the predominantly smooth-muscle arterial media at the bottom, and the thickened fibrotic intima at the top of the image. The more clear, pale-pink areas within the intima contain lipid, both intra- and extracellular. H&E stain, original magnification 4X. Figure 2. Coronary artery with a more advanced atheroma showing coalesced intimal lipid under a still thick fibrous cap. A. Microphotograph, low magnification full thickness view of a coronary artery wall cross section. Lowercase letters indicate the layers of the artery: a = adventitia, m = media, I = intima, l = lumen. Two short vertical lines delineate the markedly thinned arterial media. H&E stain, original magnification 4X. B. High magnification view of the lipid pool inside the boxed area in A. Note the needle-shaped crystals of cholesterol, most visible at the edge of the lipid pool, as indicated by the arrow. Figure 3. Coronary artery with an advanced atheroma. A. Macrophotograph of a cross section of a coronary artery showing near-total lumenal occlusion by a raised atheroma (inside box). B. Microphotograph of a cross section of the coronary artery, showing multiple raised atheromatous plaques, as indicated by Ps. Although there is still some lipid present, it has been mostly replaced by fibrosis and calcification, the latter marked by Ca in the image and indicated by blue areas or white voids where it was lost during histologic preparation.
    Keywords: Vascular Diseases, Atherosclerosis, plaques, Heart disease, thickening

  2. Macrograph: Coronary Artery Atherosclerosis (Images Only)

    show more
    Description: Figure 1. Coronary artery with early atheroma and fibrous cap formation. A. Gross macrophotograph of a longitudinally sectioned coronary artery. L indicates the lumen. The box marks a region with an early atheromatous lesion, as shown in the photomicrograph below it (B). The thin arrow to the right of the box marks a region with a more advanced lesion (see figure 2). B. Microphotograph of the early atheromatous lesion as seen in the boxed area in A. This image shows the full thickness of the coronary artery wall, from adventitia at the bottom to lumen at the top. Layers of the artery are indicated by lowercase letters on the right side of the image: l = lumen, I = intima, m = media, a = adventitia. The two yellow lines on both sides of the image mark the boundary between the predominantly smooth-muscle arterial media at the bottom, and the thickened fibrotic intima at the top of the image. The more clear, pale-pink areas within the intima contain lipid, both intra- and extracellular. H&E stain, original magnification 4X. Figure 2. Coronary artery with a more advanced atheroma showing coalesced intimal lipid under a still thick fibrous cap. A. Microphotograph, low magnification full thickness view of a coronary artery wall cross section. Lowercase letters indicate the layers of the artery: a = adventitia, m = media, I = intima, l = lumen. Two short vertical lines delineate the markedly thinned arterial media. H&E stain, original magnification 4X. B. High magnification view of the lipid pool inside the boxed area in A. Note the needle-shaped crystals of cholesterol, most visible at the edge of the lipid pool, as indicated by the arrow. Figure 3. Coronary artery with an advanced atheroma. A. Macrophotograph of a cross section of a coronary artery showing near-total lumenal occlusion by a raised atheroma (inside box). B. Microphotograph of a cross section of the coronary artery, showing multiple raised atheromatous plaques, as indicated by Ps. Although there is still some lipid present, it has been mostly replaced by fibrosis and calcification, the latter marked by Ca in the image and indicated by blue areas or white voids where it was lost during histologic preparation.
    Keywords: thickening, Vascular Diseases, plaques, Atherosclerosis, Heart disease

  3. Macrograph: Coronary Artery Atherosclerosis (Images Only)

    show more
    Description: Figure 1. Coronary artery with early atheroma and fibrous cap formation. A. Gross macrophotograph of a longitudinally sectioned coronary artery. L indicates the lumen. The box marks a region with an early atheromatous lesion, as shown in the photomicrograph below it (B). The thin arrow to the right of the box marks a region with a more advanced lesion (see figure 2). B. Microphotograph of the early atheromatous lesion as seen in the boxed area in A. This image shows the full thickness of the coronary artery wall, from adventitia at the bottom to lumen at the top. Layers of the artery are indicated by lowercase letters on the right side of the image: l = lumen, I = intima, m = media, a = adventitia. The two yellow lines on both sides of the image mark the boundary between the predominantly smooth-muscle arterial media at the bottom, and the thickened fibrotic intima at the top of the image. The more clear, pale-pink areas within the intima contain lipid, both intra- and extracellular. H&E stain, original magnification 4X. Figure 2. Coronary artery with a more advanced atheroma showing coalesced intimal lipid under a still thick fibrous cap. A. Microphotograph, low magnification full thickness view of a coronary artery wall cross section. Lowercase letters indicate the layers of the artery: a = adventitia, m = media, I = intima, l = lumen. Two short vertical lines delineate the markedly thinned arterial media. H&E stain, original magnification 4X. B. High magnification view of the lipid pool inside the boxed area in A. Note the needle-shaped crystals of cholesterol, most visible at the edge of the lipid pool, as indicated by the arrow. Figure 3. Coronary artery with an advanced atheroma. A. Macrophotograph of a cross section of a coronary artery showing near-total lumenal occlusion by a raised atheroma (inside box). B. Microphotograph of a cross section of the coronary artery, showing multiple raised atheromatous plaques, as indicated by Ps. Although there is still some lipid present, it has been mostly replaced by fibrosis and calcification, the latter marked by Ca in the image and indicated by blue areas or white voids where it was lost during histologic preparation.
    Keywords: plaques, thickening, Atherosclerosis, Vascular Diseases, Heart disease

  4. Macrograph: Coronary Artery Atherosclerosis

    show more
    Description: Figure 1. Coronary artery with early atheroma and fibrous cap formation. A. Gross macrophotograph of a longitudinally sectioned coronary artery. L indicates the lumen. The box marks a region with an early atheromatous lesion, as shown in the photomicrograph below it (B). The thin arrow to the right of the box marks a region with a more advanced lesion (see figure 2). B. Microphotograph of the early atheromatous lesion as seen in the boxed area in A. This image shows the full thickness of the coronary artery wall, from adventitia at the bottom to lumen at the top. Layers of the artery are indicated by lowercase letters on the right side of the image: l = lumen, I = intima, m = media, a = adventitia. The two yellow lines on both sides of the image mark the boundary between the predominantly smooth-muscle arterial media at the bottom, and the thickened fibrotic intima at the top of the image. The more clear, pale-pink areas within the intima contain lipid, both intra- and extracellular. H&E stain, original magnification 4X. Figure 2. Coronary artery with a more advanced atheroma showing coalesced intimal lipid under a still thick fibrous cap. A. Microphotograph, low magnification full thickness view of a coronary artery wall cross section. Lowercase letters indicate the layers of the artery: a = adventitia, m = media, I = intima, l = lumen. Two short vertical lines delineate the markedly thinned arterial media. H&E stain, original magnification 4X. B. High magnification view of the lipid pool inside the boxed area in A. Note the needle-shaped crystals of cholesterol, most visible at the edge of the lipid pool, as indicated by the arrow. Figure 3. Coronary artery with an advanced atheroma. A. Macrophotograph of a cross section of a coronary artery showing near-total lumenal occlusion by a raised atheroma (inside box). B. Microphotograph of a cross section of the coronary artery, showing multiple raised atheromatous plaques, as indicated by Ps. Although there is still some lipid present, it has been mostly replaced by fibrosis and calcification, the latter marked by Ca in the image and indicated by blue areas or white voids where it was lost during histologic preparation.
    Keywords: Heart disease, Atherosclerosis, plaques, thickening, Vascular Diseases

  5. Macrograph: Coronary Artery Atherosclerosis

    show more
    Description: Figure 1. Coronary artery with early atheroma and fibrous cap formation. A. Gross macrophotograph of a longitudinally sectioned coronary artery. L indicates the lumen. The box marks a region with an early atheromatous lesion, as shown in the photomicrograph below it (B). The thin arrow to the right of the box marks a region with a more advanced lesion (see figure 2). B. Microphotograph of the early atheromatous lesion as seen in the boxed area in A. This image shows the full thickness of the coronary artery wall, from adventitia at the bottom to lumen at the top. Layers of the artery are indicated by lowercase letters on the right side of the image: l = lumen, I = intima, m = media, a = adventitia. The two yellow lines on both sides of the image mark the boundary between the predominantly smooth-muscle arterial media at the bottom, and the thickened fibrotic intima at the top of the image. The more clear, pale-pink areas within the intima contain lipid, both intra- and extracellular. H&E stain, original magnification 4X. Figure 2. Coronary artery with a more advanced atheroma showing coalesced intimal lipid under a still thick fibrous cap. A. Microphotograph, low magnification full thickness view of a coronary artery wall cross section. Lowercase letters indicate the layers of the artery: a = adventitia, m = media, I = intima, l = lumen. Two short vertical lines delineate the markedly thinned arterial media. H&E stain, original magnification 4X. B. High magnification view of the lipid pool inside the boxed area in A. Note the needle-shaped crystals of cholesterol, most visible at the edge of the lipid pool, as indicated by the arrow. Figure 3. Coronary artery with an advanced atheroma. A. Macrophotograph of a cross section of a coronary artery showing near-total lumenal occlusion by a raised atheroma (inside box). B. Microphotograph of a cross section of the coronary artery, showing multiple raised atheromatous plaques, as indicated by Ps. Although there is still some lipid present, it has been mostly replaced by fibrosis and calcification, the latter marked by Ca in the image and indicated by blue areas or white voids where it was lost during histologic preparation.
    Keywords: thickening, plaques, Atherosclerosis, Heart disease, Vascular Diseases

  6. Macrograph: Coronary Artery Atherosclerosis

    show more
    Description: Figure 1. Coronary artery with early atheroma and fibrous cap formation. A. Gross macrophotograph of a longitudinally sectioned coronary artery. L indicates the lumen. The box marks a region with an early atheromatous lesion, as shown in the photomicrograph below it (B). The thin arrow to the right of the box marks a region with a more advanced lesion (see figure 2). B. Microphotograph of the early atheromatous lesion as seen in the boxed area in A. This image shows the full thickness of the coronary artery wall, from adventitia at the bottom to lumen at the top. Layers of the artery are indicated by lowercase letters on the right side of the image: l = lumen, I = intima, m = media, a = adventitia. The two yellow lines on both sides of the image mark the boundary between the predominantly smooth-muscle arterial media at the bottom, and the thickened fibrotic intima at the top of the image. The more clear, pale-pink areas within the intima contain lipid, both intra- and extracellular. H&E stain, original magnification 4X. Figure 2. Coronary artery with a more advanced atheroma showing coalesced intimal lipid under a still thick fibrous cap. A. Microphotograph, low magnification full thickness view of a coronary artery wall cross section. Lowercase letters indicate the layers of the artery: a = adventitia, m = media, I = intima, l = lumen. Two short vertical lines delineate the markedly thinned arterial media. H&E stain, original magnification 4X. B. High magnification view of the lipid pool inside the boxed area in A. Note the needle-shaped crystals of cholesterol, most visible at the edge of the lipid pool, as indicated by the arrow. Figure 3. Coronary artery with an advanced atheroma. A. Macrophotograph of a cross section of a coronary artery showing near-total lumenal occlusion by a raised atheroma (inside box). B. Microphotograph of a cross section of the coronary artery, showing multiple raised atheromatous plaques, as indicated by Ps. Although there is still some lipid present, it has been mostly replaced by fibrosis and calcification, the latter marked by Ca in the image and indicated by blue areas or white voids where it was lost during histologic preparation.
    Keywords: thickening, plaques, Vascular Diseases, Heart disease, Atherosclerosis